|
|
H2O + (S)-methylmalonyl-CoA <=> H+ + CoA + methylmalonate
|
3.1.2.17
(S)-methylmalonyl-CoA hydrolase
3.1.2.20
acyl-CoA hydrolase
3.1.2.4
3-hydroxyisobutyryl-CoA hydrolase
|
–
–
–
|
K
|
|
BRENDA:
BR47932;
BS401387
KEGG:
R02764
MetaCyc:
S-METHYLMALONYL-COA-HYDROLASE-RXN
SABIO-RK:
11293;
2641
|
|
|
|
methylmalonate + CoA + ATP <=> (R)-2-methylmalonyl-CoA + AMP + diphosphate
|
6.2.1
|
–
|
K
|
|
KEGG:
R03383
|
|
|
|
L-2-methyl-3-oxopropionate + NAD+ + H2O <=> methylmalonate + NADH + H+
|
1.2.1.3
aldehyde dehydrogenase (NAD+)
|
–
|
K
|
|
KEGG:
R03869
|
|
|
|
5-Methylbarbiturate + 2 H2O <=> methylmalonate + Urea
|
3.5.2.1
barbiturase
|
–
|
|
|
KEGG:
R03870
|
|
|
|
methylmalonate + H2O2 <=> L-2-methyl-3-oxopropionate + O2 + H2O
|
1.2.3.1
aldehyde oxidase
|
–
|
K
|
|
KEGG:
R03871
|
|
|
|
methylmalonate <=> L-2-methyl-3-oxopropionate
|
not assigned
|
–
|
K
|
|
KEGG:
R03872
|
|
|
|
3-Oxo-3-ureidoisobutyrate + H2O <=> methylmalonate + Urea
|
3.5.1.95
N-malonylurea hydrolase
|
–
|
K
|
|
KEGG:
R10778
|
|
|
|
methylmalonate + H+ <=> propionate + CO2
|
4.1.1.88
biotin-independent malonate decarboxylase
|
–
|
|
|
BRENDA:
BS395583
|
|
|
|
methylmalonyl-CoA + Glutarate <=> methylmalonate + glutaryl-CoA
|
2.8.3.13
succinate---hydroxymethylglutarate CoA-transferase
|
–
|
|
|
BRENDA:
BS358786
|
|
|
|
succinyl-CoA + methylmalonate <=> succinate + methylmalonyl-CoA
|
2.8.3.13
succinate---hydroxymethylglutarate CoA-transferase
|
–
|
|
|
BRENDA:
BS358776
|
|
|
|
methylmalonyl-CoA + adipate <=> methylmalonate + adipyl-CoA
|
2.8.3.13
succinate---hydroxymethylglutarate CoA-transferase
|
–
|
|
|
BRENDA:
BS358787
|
|
|
|
malonyl-CoA + methylmalonate <=> malonate + methylmalonyl-CoA
|
2.8.3.13
succinate---hydroxymethylglutarate CoA-transferase
2.8.3.3
malonate CoA-transferase
|
–
–
|
|
|
BRENDA:
BS358782
|
|
|
|
methylmalonyl-S-N-acetylcysteamine <=> N-acetylcysteamine + methylmalonate
|
3.1.2.20
acyl-CoA hydrolase
|
–
|
|
|
BRENDA:
BS405862
|
|
|
|
methylmalonyl-CoA + 3-hydroxy-3-methylglutarate <=> methylmalonate + 3-hydroxy-3-methylglutaryl-CoA
|
2.8.3.13
succinate---hydroxymethylglutarate CoA-transferase
|
–
|
|
|
BRENDA:
BS358785
|
|